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Monday, July 04, 2016

Mesothelioma, symptoms of mesothelioma lung cancer


Malignant pleural mesothelioma (MPM) is a rare tumor. The incidence of malignant pleural mesotheliaoma is: 1.25/100 000 people in Britain and 1.1 / 100 000 people in Germany. It is estimated that the prevalence will double in many countries over the next 20 years. Exposure to asbestos is a proven etiologic factor for malignant pleural mesothelioma and occupational exposure is the reason responsible for 70-80% of medical cases of malignant pleural mesothelioma.
Mesothelioma signs and symptoms



Pleural mesothelioma is a tumor originating in cells mesothelial cells that make up most serum body foils (special structures, fine, that separate cavities), including pleura, peritoneum and pericardium. Malignant mesothelioma symptoms  can be localized at a specific region or have a diffuse character.
The most common location is lung (pleural more precisely, in 90% of cases). Malignant mesothelioma lung is associated with prolonged exposure of a person to asbestos dust. Examining the numerous lots of people diagnosed with malignant mesothelioma lung, analyzing occupational exposure and individual risk factors, scientists concluded that over 75% of all cases can be linked to exposure to asbestos.
Malignant mesothelioma lung, diagnosing is often a difficult and complicated process.
Typically, individuals is presenting to doctors with dyspnea caused by pleural effusion or, more advanced, with chest pain. The diagnosis is usually suggested by imaging investigations (unilateral thickening of the pleura, the presence of pleural effusion). It is recommended that a complete case history on working conditions.


Cytology of the pleural fluid may be of diagnostic value, but the results are often inconclusive. For this reason, the gold standard is the histopathology (including immunohistochemistry). Doctors can required to make pleuroscopy, video-assisted surgery or open pleural biopsy of the pleural space Oreg fused, to obtain sufficient cellular material to achieve an accurate histopathology diagnosis. There are three major histological types (epithelial, sarcomatous and mixed), the predominant epithelium (in 60% of cases).
There are data suggesting that some proteins related to serum osteopontin mesotelina and tumor markers could be useful to support a diagnosis of mesothelioma; however, the exact role of these markers is not clearly defined.
Mesotheliaoma lung are frequently appears in men after the fifth decade of age, with a peak incidence 35-45 years after exposure to asbestos. The incidence of mesothelioma is reported to be low, approximately 1 in 100,000 people are diagnosed in time is that, annually. However, due to increasing pollution, the risk that future cases to be more frequent with 10% of all people exposed to asbestos. Patients in intensive polluted industrial areas at risk of 2 to 10 times more likely developing such a cancer.
Although the incidence is low, the prognosis of the life expectancy for an patient with malignant mesothelioma lung is always severe and unfavorable. The disease is almost always fatal. It is considered that the average survival after diagnosis is around 11 months (varies slightly depending histological sub type: 9 months for sarcomatous variant, the epithelial and 13 months to 11 months for the joint venture).


Symptoms of mesothelioma lung occur after long exposure to asbestos dust, and not less than 20- 50 years of contact.
The most common malignant mesothelioma symptoms include:
  • Abdominal bloating;
  • Abdominal pain;
  • Chest pain or discomfort;
  • Cough;
  • Shortness of breath;
  •  Neurasthenia, sweating;
  • Weight loss.
Non - pleuritice dyspnea and chest pain are the most common malignant problems in mesotheliaoma symptoms.  About 60- 90% of patients present to the doctor with these mesothelioma symptoms. Over 50% of the patients are there with pleural effusion (accumulation of fluid in the pleural space pathological) and usual to can pay all investigation patients must get them legal mesothelioma claim with help of mesothelioma cancer attorney.
In some cases the patient can be very long and asymptomatic pleural effusion, pulmonary or local changes can be observed after performing some routine investigations, or to diagnose other diseases.